SCHEMBL30849656

SCHEMBL30849656

COc1ccc(C=C2C=CC=CC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
PIM1 P11309 1/20 0.42
AKR1B1 P15121 1/20 0.42
PIM2 Q9P1W9 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP2A6 P11509 1/20 0.42
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 1/20 0.41
DYRK1A Q13627 2/20 0.41
MAPT P10636 1/20 0.41
CHRNA7 P36544 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
TRPA1 O75762 1/20 0.40
RELA Q04206 1/20 0.40
METAP1 P53582 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28182498 0.76 PTPN1 (0.50) CYP1A2NPC1RAB9AALDH1A1LMNA
SCHEMBL18315266 0.75 ALDH1A1 (0.50) CYP1A2PIM1AKR1B1PIM2NPC1
SCHEMBL21616789 0.74 NPC1 (0.42) NPC1RAB9AMAPTGSK3BCYP19A1
Methylamine SCHEMBL28226585 0.74 ALDH1A1 (0.35) CYP1A2PIM1PIM2ALDH1A1LMNA
SCHEMBL28308866 0.70 CA1 (0.33) TP53CA1CA2CA9PTGS2
SCHEMBL28248584 0.69 ALDH1A1 (0.35) CYP1A2PIM1PIM2ALDH1A1LMNA
SCHEMBL28693827 0.69 CYP1A2 (0.56) CYP1A2PIM1AKR1B1PIM2NPC1
SCHEMBL16773077 0.64 CYP1A2 (0.56) CYP1A2PIM1AKR1B1PIM2NPC1
SCHEMBL4881152 0.64 RELA (0.81) CYP1A2NPC1RAB9AALDH1A1LMNA
SCHEMBL699457 0.64 RELA (0.81) CYP1A2NPC1RAB9AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624092-A Method for preparing N-diaryl methyl substituted-2-amino furan compound 湖南理工学院 2024-03-01 CN claimed