Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477470 | 1.00 | PPARG (0.54) | PPARGPPARARIPK1ACP3LMNA | |
| SCHEMBL5835025 | 1.00 | PPARG (0.54) | PPARGPPARARIPK1ACP3LMNA | |
| SCHEMBL936320 | 0.95 | PPARG (0.58) | PPARGPPARARIPK1ACP3LMNA | |
| SCHEMBL936318 | 0.95 | PPARG (0.50) | PPARGPPARARIPK1ACP3LMNA | |
| SCHEMBL29861111 | 0.90 | MMP12 (0.50) | PPARGPPARARIPK1ACP3LMNA | |
| SCHEMBL4575395 | 0.89 | RIPK1 (0.52) | RIPK1ACP3LMNASLC6A2SLC6A4 | |
| SCHEMBL9460360 | 0.88 | ADRA1A (0.56) | LMNASLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL26326703 | 0.88 | MMP12 (0.53) | PPARGPPARARIPK1ACP3LMNA | |
| SCHEMBL19152252 | 0.88 | MMP12 (0.57) | PPARGPPARARIPK1ACP3LMNA | |
| SCHEMBL1837304 | 0.88 | MEN1 (0.54) | PPARGPPARARIPK1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096047-B | Preparation method of (1R) -1, 3-diphenyl-1-propanol | 湖北远大富驰医药化工股份有限公司 | 2021-08-10 | — | — | CN | claimed |
| CN-109096047-A | The preparation method of one kind (1R) -1,3- diphenyl -1- propyl alcohol | 湖北远大富驰医药化工股份有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-117865776-A | Method for directly converting aromatic alkyne into chiral alcohol by one-pot method | 三峡大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-109096047-B | Preparation method of (1R) -1, 3-diphenyl-1-propanol | 湖北远大富驰医药化工股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-109096047-B | Preparation method of (1R) -1, 3-diphenyl-1-propanol | 湖北远大富驰医药化工股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-109096047-B | Preparation method of (1R) -1, 3-diphenyl-1-propanol | 湖北远大富驰医药化工股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-108017518-B | 1, 3-diphenyl-1-propanol and preparation method thereof | 湖北远大富驰医药化工股份有限公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-109096047-A | The preparation method of one kind (1R) -1,3- diphenyl -1- propyl alcohol | 湖北远大富驰医药化工股份有限公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-109096047-A | The preparation method of one kind (1R) -1,3- diphenyl -1- propyl alcohol | 湖北远大富驰医药化工股份有限公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-109096047-A | The preparation method of one kind (1R) -1,3- diphenyl -1- propyl alcohol | 湖北远大富驰医药化工股份有限公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-108017518-A | 1,3- diphenyl -1- propyl alcohol and preparation method thereof | 湖北远大富驰医药化工股份有限公司 | 2018-05-11 | — | — | CN | disclosed |
| US-6291510-B1 | N-LINKED 1,2-DIKETO PROLYL ESTER COMPOUND OR A N-LINKED 1,2-DIKETO PROLYL AMIDE COMPOUND, WHEREIN SAID ESTER COMPOUND OR SAID AMIDE COMPOUND IS NON-IMMUNOSUPPRESSIVE. | GPI NIL HOLDINGS, INC. | 2001-09-18 | — | — | US | disclosed |
| US-6150527-A | Synthetic multimerizing agents | ARIAD PHARMACEUTICALS, INC. (US) | 2000-11-21 | — | — | US | disclosed |
| US-6133456-A | DIMERS OF THE MACROCYCLIC NATURAL PRODUCT, FK506, COVALENTLY ATTACHED TO EACH OTHER VIA A SYNTHETIC LINKER MOIETY | ARIAD GENE THERAPEUTICS, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0888303-A1 | SYNTHETIC DERIVATIVES OF RAPAMYCIN AS MULTIMERIZING AGENTS FOR CHIMERIC PROTEINS WITH IMMUNOPHILIN-DERIVED DOMAINS | ARIAD GENE THERAPEUTICS, INC. (US) | 1999-01-07 | — | — | EP | disclosed |
| EP-0776327-A4 | NEW MULTIMERIZING AGENTS | ARIAD GENE THERAPEUTICS INC (US) | 1997-12-10 | — | — | EP | disclosed |
| WO-1997031898-A1 | SYNTHETIC DERIVATIVES OF RAPAMYCIN AS MULTIMERIZING AGENTS FOR CHIMERIC PROTEINS WITH IMMUNOPHILIN-DERIVED DOMAINS | ARIAD GENE THERAPEUTICS, INC. (US) | 1997-09-04 | — | — | WO | disclosed |
| EP-0776327-A1 | NEW MULTIMERIZING AGENTS | ARIAD GENE THERAPEUTICS, INC. (US) | 1997-06-04 | — | — | EP | disclosed |
| US-5614547-A | Small molecule inhibitors of rotamase enzyme | GUILFORD PHARMACEUTICALS INC. (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1996006097-A1 | NEW MULTIMERIZING AGENTS | ARIAD GENE THERAPEUTICS, INC. (US) | 1996-02-29 | — | — | WO | disclosed |