SCHEMBL30849697

SCHEMBL30849697

CCCN(CCC)C(=O)Cc1c(-c2ccc([18F])cc2)nc2c(Cl)cc(Cl)cn12

nearest known ligand 0.86

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TSPO P30536 6/20 0.86
▸ GMNN O75496 1/20 0.86
▸ LMNA P02545 1/20 0.86
▸ POLB P06746 1/20 0.86
▸ CYP3A4 P08684 1/20 0.86
▸ BLM P54132 1/20 0.86
▸ NPSR1 Q6W5P4 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22345172 1.00 TSPO (0.86) TSPOGMNNLMNAPOLBCYP3A4
SCHEMBL30849696 1.00 TSPO (0.86) TSPOGMNNLMNAPOLBCYP3A4
SCHEMBL30849701 1.00 TSPO (0.86) TSPOGMNNLMNAPOLBCYP3A4
Alpdem SCHEMBL1230701 0.93 TSPO (1.00) TSPOGMNNLMNAPOLBCYP3A4
SCHEMBL22627637 0.92 TSPO (0.73) TSPOGMNNLMNAPOLBCYP3A4
SCHEMBL22627545 0.92 TSPO (0.90) TSPOGMNNLMNAPOLBCYP3A4
SCHEMBL21191657 0.90 TSPO (0.86) TSPOGMNNLMNAPOLBCYP3A4
SCHEMBL27218941 0.88 TSPO (0.80) TSPOGMNNLMNAPOLBCYP3A4
SCHEMBL22612467 0.88 TSPO (0.83) TSPOGMNNLMNAPOLBCYP3A4
SCHEMBL21191506 0.88 TSPO (0.83) TSPOGMNNLMNAPOLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240156997-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-05-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240156997-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR TSPO, FABP7, SLC46A1 TSPO 1/4885GMNN 3686/4885LMNA 4272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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