SCHEMBL20022331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30849844	0.81	KDM4E (0.43)	DAOKDM4EMAPTMEN1ALDH1A1
	SCHEMBL25675331	0.74	ALDH1A1 (0.33)	ALDH1A1
	SCHEMBL18889225	0.74	KDM4E (0.50)	DAOKDM4EMAPTMEN1ALDH1A1
	SCHEMBL26949623	0.72	STING1 (0.54)	STING1GPR35LMNAPKM
	SCHEMBL30682860	0.72	STING1 (0.54)	STING1GPR35LMNAPKM
	SCHEMBL7433969	0.72	STING1 (0.72)	KDM4EALDH1A1ICAM1SELESTING1
	SCHEMBL20022327	0.72	STING1 (0.56)	KMT2ASTING1
	SCHEMBL24721595	0.71	PLK4 (0.59)	DAOKDM4EMAPTMEN1ALDH1A1
	SCHEMBL25274256	0.71	STING1 (0.53)	STING1
	SCHEMBL10221595	0.69	GPR35 (0.63)	DAOKDM4EMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.