Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 13/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 13/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13860587 | 0.75 | CYP1A2 (0.49) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL27610277 | 0.73 | TSHR (0.49) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL24690574 | 0.72 | — | — | |
| SCHEMBL461271 | 0.72 | — | — | |
| SCHEMBL2644600 | 0.71 | — | — | |
| SCHEMBL25815441 | 0.70 | BAZ2B (0.53) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL31336826 | 0.69 | GABRG2 (0.36) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL22190961 | 0.69 | HPGDS (0.39) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL7421479 | 0.69 | GABRG2 (0.40) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL28761548 | 0.69 | HPGDS (0.39) | GABRG2GABRB3GABRA5GABRA1GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |