SCHEMBL30850484

SCHEMBL30850484

c1nc2cnc(-c3cncc(C4CC4)c3)nc2[nH]1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR55 Q9Y2T6 1/20 0.34
CYP11B2 P19099 2/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
PIM1 P11309 2/20 0.32
PIM3 Q86V86 2/20 0.32
PIM2 Q9P1W9 2/20 0.32
ACVR1 Q04771 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30677421 0.77 GBA1 (0.38) CYP11B2
SCHEMBL30850720 0.77 PIK3CA (0.42) CYP11B2
SCHEMBL30850641 0.75 AXL (0.41) CYP11B2PIM1PIM3
SCHEMBL30850562 0.74 CYP11B1 (0.42) CYP11B2
SCHEMBL31547968 0.73 MAPK1 (0.41) ACVR1
SCHEMBL30850608 0.70 XDH (0.40) CYP11B2PRMT5WDR77
SCHEMBL30677345 0.70 QPCT (0.50)
SCHEMBL3027716 0.70 QPCT (0.50)
SCHEMBL680853 0.68 NPC1 (0.45)
SCHEMBL4875480 0.68 KDM4E (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240116975-A1 ADENOSINE A3 RECEPTOR AGONISTS, PREPARATION METHODS AND USES THEREOF ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) 2024-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240116975-A1 ADENOSINE A3 RECEPTOR AGONISTS, PREPARATION METHODS AND USES THEREOF ADORA3, ADORA2A, ADORA2B GPR55 348/4885CYP11B2 746/4885PRMT5 3643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.