Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 9/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.35 |
| ▸ | OXTR | P30559 | 2/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30850824 | 0.85 | AVPR2 (0.34) | FGFR4AVPR2OXTRAVPR1ASMYD3 | |
| SCHEMBL29860313 | 0.84 | MPO (0.37) | FGFR4NPC1RAB9AITGAVITGB6 | |
| SCHEMBL23527756 | 0.82 | FGFR4 (0.36) | FGFR4ITGAV | |
| SCHEMBL20517697 | 0.81 | NOTUM (0.41) | FGFR4 | |
| SCHEMBL29416391 | 0.81 | MPO (0.38) | FGFR4NPC1RAB9AITGAVITGB6 | |
| SCHEMBL21314546 | 0.79 | FGFR4 (0.38) | FGFR4KMT2ASMN1; SMN2ITGAV | |
| SCHEMBL31076000 | 0.78 | MPO (0.37) | FGFR4NPC1RAB9AITGAVITGB6 | |
| SCHEMBL12807163 | 0.78 | MPO (0.38) | FGFR4AVPR2OXTRAVPR1ANPC1 | |
| SCHEMBL14380644 | 0.78 | MPO (0.38) | FGFR4NPC1RAB9AITGAVITGB6 | |
| SCHEMBL29922126 | 0.77 | KDM4E (0.34) | FGFR4ITGAVITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884661-B2 | 3-substituted propionic acids as αV integrin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884661-B2 | 3-substituted propionic acids as αV integrin inhibitors | ITGB3, ITGB1, ITGAV | FGFR4 671/4885AVPR2 776/4885OXTR 2315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.