Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957491 | 0.81 | PNP (0.39) | PNPALDH1A1GDAMEN1KMT2A | |
| SCHEMBL27461265 | 0.78 | PNP (0.38) | PNPALDH1A1GDA | |
| SCHEMBL28432887 | 0.76 | PNP (0.38) | PNPALDH1A1GDAMEN1KMT2A | |
| SCHEMBL389888 | 0.76 | PNP (0.46) | PNPALDH1A1 | |
| SCHEMBL28303905 | 0.76 | PNP (0.39) | PNPALDH1A1GDAMEN1KMT2A | |
| SCHEMBL2352519 | 0.74 | PNP (0.43) | PNPALDH1A1GDAMEN1KMT2A | |
| SCHEMBL28746160 | 0.73 | PNP (0.36) | PNPALDH1A1GDAMEN1KMT2A | |
| SCHEMBL8519587 | 0.72 | PNP (0.36) | PNPALDH1A1GDAMEN1KMT2A | |
| SCHEMBL618978 | 0.72 | PNP (0.44) | PNPALDH1A1GDAMEN1KMT2A | |
| SCHEMBL8356642 | 0.72 | PNP (0.41) | PNPALDH1A1GDAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180055868-A1 | METHODS AND COMPOSITIONS FOR STIMULATING BONE REGENERATION | NEW YORK UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| US-20160262894-A1 | TISSUE REPAIR DEVICES AND SCAFFOLDS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2016-09-15 | — | — | US | disclosed |
| WO-2015065819-A1 | TISSUE REPAIR DEVICES AND SCAFFOLDS | NEW YORK UNIVERSITY (US) | 2015-05-07 | — | — | WO | disclosed |
| US-20150011496-A1 | METHODS AND COMPOSITIONS FOR STIMULATING BONE REGENERATION | NEW YORK UNIVERSITY | 2015-01-08 | — | — | US | disclosed |
| WO-2013126545-A1 | METHODS AND COMPOSITIONS FOR STIMULATING BONE REGENERATION | NEW YORK UNIVERSITY (US) | 2013-08-29 | — | — | WO | disclosed |
| US-7795427-B2 | Methods for inhibiting osteoclast differentiation, formation, or function and for increasing bone mass | NEW YORK UNIVERSITY (US) | 2010-09-14 | — | — | US | disclosed |
| WO-2007095161-A2 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS ASSOCIATED WITH INCREASED BONE TURNOVER AND OSTEOPENIA | NEW YORK UNIVERSITY (US) | 2007-08-23 | — | — | WO | disclosed |
| US-20070191279-A1 | Methods and compositions for treating disorders associated with increased bone turnover and osteopenia | CRONSTEIN BRUCE N | 2007-08-16 | — | — | US | disclosed |
| CN-1251676-C | Phenyl xanthine derivative | GLAXO GROUP LTD (GB) | 2006-04-19 | — | — | CN | disclosed |
| CN-1515571-A | Phenyl xanthine derivative | — | 2004-07-28 | — | — | CN | disclosed |
| US-6545002-B1 | Treating asthma, diarrhea, insulin resistance, diabetes, ischemia/reprefusion injuries, diabetic retinopathy or hyperbaric oxygen-induced retinopathy | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2003-04-08 | — | — | US | disclosed |
| EP-1192158-A2 | SUBSTITUTED 8-PHENYLXANTHINES USEFUL AS ANTAGONISTS OF A 2B? ADENOSINE RECEPTORS | University of Virginia Patent Foundation (US) | 2002-04-03 | — | — | EP | disclosed |
| US-6365593-B2 | USING CONCENTRATION OF URINE SAMPLING | REPLIGEN CORPORATION | 2002-04-02 | — | — | US | disclosed |
| US-20020019407-A1 | Methylxanthines in the diagnosis and treatment of autistic disorder | REPLIGEN CORPORATION | 2002-02-14 | — | — | US | disclosed |
| CN-1323309-A | Phenyl xanthine derivatives | GLAXO GROUP LTD (GB) | 2001-11-21 | — | — | CN | disclosed |
| WO-2001079837-A1 | METHYLXANTHINES IN THE DIAGNOSIS AND TREATMENT OF AUTISTIC DISORDER | REPLIGEN CORPORATION (US) | 2001-10-25 | — | — | WO | disclosed |
| WO-2000073307-A2 | SUBSTITUTED 8-PHENYLXANTHINES USEFUL AS ANTAGONISTS OF A2B ADENOSINE RECEPTORS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2000-12-07 | — | — | WO | disclosed |
| US-5453426-A | Sulfur-containing xanthine derivatives as adenosine antagonists | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-09-26 | — | — | US | disclosed |
| US-4968672-A | DRUG DELIVERY; DIURETICS, KIDNEY DISORDERS, HYPOTENSIVE AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1990-11-06 | — | — | US | disclosed |
| WO-1990012797-A1 | SULFER-CONTAINING XANTHINE DERIVATIVES AS ADENOSIN ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1990-11-01 | — | — | WO | disclosed |