Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LIG1 | P18858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085105 | 0.81 | PNP (0.38) | PNPGDAALDH1A1KDM4EMEN1 | |
| SCHEMBL389888 | 0.78 | PNP (0.46) | PNPALDH1A1 | |
| SCHEMBL4560085 | 0.77 | GDA (0.53) | PNPGDAALDH1A1LIG1KDM4E | |
| SCHEMBL27461265 | 0.76 | PNP (0.38) | PNPGDAALDH1A1 | |
| SCHEMBL8519587 | 0.76 | PNP (0.36) | PNPGDAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28079039 | 0.75 | GDA (0.51) | PNPGDAALDH1A1LIG1KDM4E | |
| SCHEMBL27708662 | 0.75 | GDA (0.51) | PNPGDAALDH1A1LIG1KDM4E | |
| Ammonia Solution, Strong SCHEMBL28309009 | 0.75 | GDA (0.51) | PNPGDAALDH1A1LIG1KDM4E | |
| SCHEMBL9949248 | 0.73 | PNP (0.41) | PNPGDAALDH1A1KDM4EMEN1 | |
| SCHEMBL618978 | 0.73 | PNP (0.44) | PNPGDAALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393662-B2 | Human EPO mimetic hinge core mimetibodies, compositions, methods and uses | CENTOCOR, INC. (US) | 2008-07-01 | — | — | US | disclosed |
| US-20060051844-A1 | Human EPO mimetic hinge core mimetibodies, compositions, methods and uses | CNA DEVELOPMENT GMBH (CH) | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060051844-A1 | Human EPO mimetic hinge core mimetibodies, compositions, methods and uses | EPOR, GHITM, HBB | PNP 2055/4885GDA 1282/4885ALDH1A1 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.