SCHEMBL389888

SCHEMBL389888

O=c1[nH]c(=O)c2ncn(OP(=O)(O)O)c2[nH]1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PNP P00491 8/20 0.46
▸ ALDH1A1 P00352 1/20 0.35
▸ HPRT1 P00492 10/20 0.33
▸ POLB P06746 2/20 0.33
▸ POLG P54098 2/20 0.33
▸ POLA1 P09884 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1820814 0.87 ALDH1A1 (0.49) PNPALDH1A1
SCHEMBL28335557 0.78 ALDH1A1 (0.44) PNPALDH1A1POLBPOLGPOLA1
SCHEMBL4957491 0.78 PNP (0.39) PNPALDH1A1
SCHEMBL3085105 0.76 PNP (0.38) PNPALDH1A1
SCHEMBL28333212 0.76 ALDH1A1 (0.42) PNPALDH1A1POLBPOLGPOLA1
SCHEMBL27461265 0.75 PNP (0.38) PNPALDH1A1
SCHEMBL6680764 0.73 HPRT1 (0.38) PNPALDH1A1HPRT1
SCHEMBL618978 0.72 PNP (0.44) PNPALDH1A1POLB
SCHEMBL27947874 0.71 HPRT1 (0.54) PNPHPRT1POLBPOLGPOLA1
SCHEMBL2352519 0.71 PNP (0.43) PNPALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220218731-A1 COMBINATION THERAPIES FOR CANCER TREATMENT CLEAR CREEK BIO INC (US) 2022-07-14 — — US claimed
WO-2020236502-A1 COMBINATION THERAPIES FOR CANCER TREATMENT Clear Creek Bio, Inc. (US) 2020-11-26 — — WO claimed
US-20260116994-A1 RECOMBINANT MONOCLONAL ANTIBODIES AND CORRESPONDING ANTIGENS FOR COLON AND PANCREATIC CANCERS PREC BIOLOGICS INC (US) 2026-04-30 — — US disclosed
US-12584099-B2 Method for preparing cultures of lactic acid bacteria CHR. HANSEN A/S (DK) 2026-03-24 — — US disclosed
US-20260015432-A1 RECOMBINANT MONOCLONAL ANTIBODIES AND CORRESPONDING ANTIGENS FOR COLON AND PANCREATIC CANCERS PREC BIOLOGICS INC (US) 2026-01-15 — — US disclosed
US-12460013-B2 Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers PRECISION BIOLOGICS, INC. (US) 2025-11-04 — — US disclosed
US-12344676-B2 Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers PRECISION BIOLOGICS, INC. (US) 2025-07-01 — — US disclosed
WO-2025105871-A1 GENE EDITING TREATMENT METHOD AND THERAPEUTIC AGENT FOR RETINITIS PIGMENTOSA 재단법인 아산사회복지재단 2025-05-22 — — WO disclosed
US-20250049753-A1 METHODS AND COMPOSITIONS FOR DELIVERING MYCOPHENOLIC ACID ACTIVE AGENTS TO NON-HUMAN MAMMALS OKAVA PHARMACEUTICALS INC (US) 2025-02-13 — — US disclosed
US-20240368532-A1 METHOD FOR PREPARING CULTURES OF LACTIC ACID BACTERIA CHR. HANSEN A/S (DK) 2024-11-07 — — US disclosed
US-20240343825-A1 RECOMBINANT MONOCLONAL ANTIBODIES AND CORRESPONDING ANTIGENS FOR COLON AND PANCREATIC CANCERS PREC BIOLOGICS INC (US) 2024-10-17 — — US disclosed
WO-1989011538-A1 PLATELET-SPECIFIC CHIMERIC IMMUNOGLOBULIN CENTOCOR, INC. (US) 1989-11-30 — — WO disclosed
WO-1989008716-A1 NOVEL RECOMBINANT VACCINIA VIRUS EXPRESSION VECTORS AND METHOD OF SELECTING SAME THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH (US) 1989-09-21 — — WO disclosed
EP-0322417-A1 EMPTY VIRAL CAPSID VACCINES APPLIED BIOTECHNOLOGY, INC. (US) 1989-07-05 — — EP disclosed
WO-1989004872-A1 IMMUNOREACTIVE HETEROCHAIN ANTIBODIES CENTOCOR, INC. (US) 1989-06-01 — — WO disclosed
WO-1988009181-A2 MONOCLONAL ANTIBODIES NEUTRALIZING HIV-1 TANOX BIOSYSTEMS, INC. (US) 1988-12-01 — — WO disclosed
WO-1988002026-A1 EMPTY VIRAL CAPSID VACCINES APPLIED BIOTECHNOLOGY, INC. (US) 1988-03-24 — — WO disclosed
WO-1988002022-A1 RECOMBINANT POXVIRUSES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 1988-03-24 — — WO disclosed
EP-0256654-A2 Chimeric murine/human immunoglobulin specific for tumour-associated 17-1A Antigen CENTOCOR, INC. (US) 1988-02-24 — — EP disclosed
US-4550186-A ANTITUMOR, ANTILIPEMIC, ANTIINFLAMMATORY, AND ANTIARTHRITIC AGENTS DUKE UNIVERSITY (US) 1985-10-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116994-A1 RECOMBINANT MONOCLONAL ANTIBODIES AND CORRESPONDING ANTIGENS FOR COLON AND PANCREATIC CANCERS IGSF11, IGLV6-57, VSIG8 PNP 3511/4885ALDH1A1 4490/4885HPRT1 4342/4885
US-20250049753-A1 METHODS AND COMPOSITIONS FOR DELIVERING MYCOPHENOLIC ACID ACTIVE AGENTS TO NON-HUMAN MAMMALS CD47, TPMT, HLA-C PNP 210/4885ALDH1A1 1644/4885HPRT1 387/4885
US-20260015432-A1 RECOMBINANT MONOCLONAL ANTIBODIES AND CORRESPONDING ANTIGENS FOR COLON AND PANCREATIC CANCERS VIP, IAPP, RNASE1 PNP 948/4885ALDH1A1 4201/4885HPRT1 4283/4885
US-12584099-B2 Method for preparing cultures of lactic acid bacteria LCT, S100A10, RPLP0 PNP 1100/4885ALDH1A1 1139/4885HPRT1 1530/4885
US-20220218731-A1 COMBINATION THERAPIES FOR CANCER TREATMENT PCK2, PC, FOLR2 PNP 1680/4885ALDH1A1 146/4885HPRT1 978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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