Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957491 | 0.76 | PNP (0.39) | PNPMEN1KMT2ASMN1; SMN2GDA | |
| SCHEMBL8884657 | 0.76 | PNP (0.51) | PNPMEN1KMT2AHTTGDA | |
| SCHEMBL60160 | 0.73 | PNP (0.47) | PNPMEN1KMT2ASMN1; SMN2GDA | |
| SCHEMBL3085105 | 0.72 | PNP (0.38) | PNPMEN1KMT2AGDAKDM4E | |
| SCHEMBL27461265 | 0.70 | PNP (0.38) | PNPGDAALDH1A1 | |
| SCHEMBL10001264 | 0.70 | MEN1 (0.45) | PNPMEN1KMT2ASMN1; SMN2GDA | |
| SCHEMBL389888 | 0.69 | PNP (0.46) | PNPHPRT1ALDH1A1 | |
| SCHEMBL4560085 | 0.68 | GDA (0.53) | PNPMAPK1MEN1KMT2AMAPT | |
| SCHEMBL7326970 | 0.68 | PNP (0.48) | PNPMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL380137 | 0.67 | PNP (0.50) | PNPKMT2ASMN1; SMN2GDAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888811-A | ISOLATED NUCLEIC ACIDS; GENETIC ENGINEERING | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-30 | — | — | US | disclosed |