Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.67 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.67 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786755 | 1.00 | CRBN (0.67) | CRBNDDB1CHRNB2CHRNA4POLB | |
| SCHEMBL31109516 | 1.00 | CRBN (0.67) | CRBNDDB1CHRNB2CHRNA4POLB | |
| SCHEMBL26746596 | 0.86 | DDB1 (0.49) | CRBNDDB1CHRNB2CHRNA4POLB | |
| SCHEMBL19586225 | 0.80 | CRBN (1.00) | CRBNDDB1POLB | |
| SCHEMBL31704153 | 0.80 | CRBN (1.00) | CRBNDDB1POLB | |
| SCHEMBL2107934 | 0.80 | CRBN (1.00) | CRBNDDB1POLB | |
| SCHEMBL31704110 | 0.80 | CRBN (1.00) | CRBNDDB1POLB | |
| SCHEMBL31699350 | 0.79 | CHRNB2 (0.56) | CHRNB2CHRNA4POLBKDM4ECYP3A4 | |
| SCHEMBL24832965 | 0.77 | CRBN (0.60) | CRBNDDB1POLB | |
| SCHEMBL13035251 | 0.76 | CHRNB2 (0.56) | CRBNDDB1CHRNB2CHRNA4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813307-A | Difunctional degradants of interleukin-1 receptor related kinase and therapeutic uses thereof | 新锐思生物制药股份有限公司 | 2024-04-02 | — | — | CN | disclosed |