Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | LGMN | Q99538 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30851493 | 0.90 | LGMN (0.43) | ACELGMNHPGDDPP4CPT2 | |
| SCHEMBL24980252 | 0.85 | LGMN (0.56) | F2ACELGMNDPP4PREP | |
| SCHEMBL30851484 | 0.81 | MMP8 (0.56) | LGMN | |
| SCHEMBL30851483 | 0.80 | LGMN (0.64) | LGMNSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30851485 | 0.80 | LGMN (0.43) | F2LGMN | |
| SCHEMBL30851487 | 0.80 | LGMN (0.61) | LGMN | |
| SCHEMBL30851510 | 0.79 | LGMN (0.39) | F2ACELGMNNPC1CPT2 | |
| SCHEMBL30851482 | 0.78 | FKBP1A (0.49) | LGMN | |
| SCHEMBL3144462 | 0.76 | ACE (0.64) | F2ACEHPGDSMN1; SMN2NPC1 | |
| SCHEMBL5742165 | 0.76 | ACE (0.64) | F2ACEHPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813284-A | Halogenated acethydrazide as AEP inhibitor | 豪夫迈·罗氏有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117813284-A | Halogenated acethydrazide as AEP inhibitor | 豪夫迈·罗氏有限公司 | 2024-04-02 | — | — | CN | disclosed |