Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.40 |
| ▸ | ATR | Q13535 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19743909 | 1.00 | NPSR1 (0.44) | NPSR1MAPKAPK2ATRPRKCIL3MBTL1 | |
| SCHEMBL30852257 | 0.89 | NPSR1 (0.42) | NPSR1MAPKAPK2ATRPRKCIL3MBTL1 | |
| Lithium Ion SCHEMBL19743877 | 0.83 | ATR (0.37) | MAPKAPK2ATRPRKCIDHFRALDH1A1 | |
| SCHEMBL3868054 | 0.83 | GABRP (0.41) | MAPKAPK2ATRPRKCIDHFRGABRA1 | |
| SCHEMBL7456521 | 0.83 | ACVR1 (0.40) | NPSR1MAPKAPK2ATRL3MBTL1KDM4E | |
| SCHEMBL25206722 | 0.82 | NPSR1 (0.42) | NPSR1L3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL25281688 | 0.81 | NPSR1 (0.39) | NPSR1MAPKAPK2ATRKDM4EALDH1A1 | |
| SCHEMBL19718220 | 0.79 | NPSR1 (0.50) | NPSR1ATRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL261742 | 0.77 | ATR (0.54) | NPSR1ATRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL262307 | 0.77 | GRM5 (0.54) | NPSR1ATRPRKCIL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |