Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30852147 | 0.89 | NPSR1 (0.44) | NPSR1KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL19743909 | 0.89 | NPSR1 (0.44) | NPSR1KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL14720728 | 0.83 | APP (0.45) | NPSR1KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL14720919 | 0.82 | NPSR1 (0.38) | NPSR1KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL3979134 | 0.81 | GABRP (0.41) | ALDH1A1MAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL1680511 | 0.80 | PLAU (0.53) | NPSR1KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL25399004 | 0.78 | NPSR1 (0.47) | NPSR1KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL12248189 | 0.78 | NPSR1 (0.47) | NPSR1KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL25206722 | 0.77 | NPSR1 (0.42) | NPSR1KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL260853 | 0.77 | NPSR1 (0.45) | NPSR1KDM4EALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |