Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 7/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30851883 | 0.83 | CYP11B1 (0.46) | RBP4CACNA1CKDM4E | |
| SCHEMBL17730953 | 0.83 | BRD4 (0.46) | KDM4EALDH1A1KMT2ATDP1L3MBTL1 | |
| SCHEMBL28171054 | 0.79 | JAK2 (0.43) | KDM4ETDP1L3MBTL1TP53HCRTR2 | |
| SCHEMBL180554 | 0.77 | IDO1 (0.49) | KDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10188552 | 0.77 | DGAT1 (0.46) | HTR2CKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL17505317 | 0.76 | RBP4 (0.69) | RBP4L3MBTL1 | |
| SCHEMBL30852120 | 0.75 | CYP11B1 (0.41) | RBP4 | |
| SCHEMBL28713042 | 0.75 | HTR2C (0.63) | RBP4HTR2CGAATDP1 | |
| SCHEMBL5007618 | 0.74 | HTR2C (0.75) | RBP4HTR2CGAATDP1 | |
| SCHEMBL19984879 | 0.74 | CYP11B1 (0.56) | CACNA1CKDM4EALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |