Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | RBP4 | P02753 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30852120 | 0.92 | CYP11B1 (0.41) | CYP11B1CYP11B2RBP4JAK2JAK1 | |
| SCHEMBL30852256 | 0.83 | RBP4 (0.48) | RBP4KDM4ECACNA1C | |
| SCHEMBL30851954 | 0.82 | JAK2 (0.42) | CYP11B1CYP11B2JAK2JAK1TYK2 | |
| SCHEMBL17731272 | 0.76 | DGAT1 (0.48) | JAK2JAK1TYK2JAK3KDM4E | |
| SCHEMBL17731258 | 0.75 | TSHR (0.48) | CYP11B2JAK2JAK1TYK2JAK3 | |
| SCHEMBL10188552 | 0.73 | DGAT1 (0.46) | CYP11B1CYP11B2JAK2JAK1TYK2 | |
| SCHEMBL21836594 | 0.73 | JAK2 (0.46) | JAK2JAK1TYK2JAK3KDM4E | |
| SCHEMBL19899845 | 0.73 | JAK2 (0.46) | JAK2JAK1TYK2JAK3KDM4E | |
| SCHEMBL19900749 | 0.73 | JAK2 (0.46) | JAK2JAK1TYK2JAK3KDM4E | |
| SCHEMBL21836492 | 0.72 | CCRL2 (0.53) | CYP11B1CYP11B2JAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |