SCHEMBL30852376

SCHEMBL30852376

Nc1cccc(Cl)c1C(=O)C[C@H](N)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 3/20 0.51
KDM4E B2RXH2 1/20 0.50
HIF1A Q16665 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
GRIK1 P39086 3/20 0.45
GRIK2 Q13002 2/20 0.45
FEN1 P39748 1/20 0.42
JAK1 P23458 1/20 0.41
KYNU Q16719 2/20 0.41
ITGB2 P05107 1/20 0.40
ICAM1 P05362 1/20 0.40
ITGAL P20701 1/20 0.40
P2RX7 Q99572 1/20 0.39
ALDH1A1 P00352 1/20 0.39
KIF11 P52732 1/20 0.39
ALPI P09923 1/20 0.39
PKM P14618 1/20 0.39
PTGS1 P23219 1/20 0.39
XIAP P98170 1/20 0.39
SLC7A5 Q01650 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31520067 1.00 KMO (0.51) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL30852338 1.00 KMO (0.51) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL1305231 1.00 KMO (0.51) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL975884 0.83 KDM4E (0.63) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL9039079 0.81 KDM4E (0.50) KMOKDM4EHIF1ATDP1KYNU
SCHEMBL9340027 0.81 KDM4E (0.47) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL31520062 0.78 KDM4E (0.70) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL31520061 0.78 KDM4E (0.70) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL7415550 0.78 KMO (0.51) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL30852411 0.78 KDM4E (0.70) KMOKDM4EHIF1ATDP1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120019060-A Compounds and their use for filtering ultraviolet and/or high-energy visible light 索利奥美公司 2025-05-16 CN claimed
EP-4587007-A2 COMPOUNDS AND THEIR USE IN FILTERING ULTRAVIOLET AND/OR HIGH-ENERGY VISIBLE LIGHT Soliome, Inc. (US) 2025-07-23 EP disclosed
CN-120019060-A Compounds and their use for filtering ultraviolet and/or high-energy visible light 索利奥美公司 2025-05-16 CN disclosed
WO-2024059119-A2 COMPOUNDS AND THEIR USE IN FILTERING ULTRAVIOLET AND/OR HIGH-ENERGY VISIBLE LIGHT SOLIOME, INC. (US) 2024-03-21 WO disclosed