Sugi Predict

Sugi Predict / Compounds / SCHEMBL1305231

SCHEMBL1305231

SCHEMBL1305231

Nc1cccc(Cl)c1C(=O)C[C@H](N)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMO O15229 3/20 0.51
▸ KDM4E B2RXH2 1/20 0.50
▸ HIF1A Q16665 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ GRIK1 P39086 3/20 0.45
▸ GRIK2 Q13002 2/20 0.45
▸ FEN1 P39748 1/20 0.42
▸ JAK1 P23458 1/20 0.41
▸ KYNU Q16719 2/20 0.41
▸ ITGB2 P05107 1/20 0.40
▸ ICAM1 P05362 1/20 0.40
▸ ITGAL P20701 1/20 0.40
▸ P2RX7 Q99572 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ KIF11 P52732 1/20 0.39
▸ ALPI P09923 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ PTGS1 P23219 1/20 0.39
▸ XIAP P98170 1/20 0.39
▸ SLC7A5 Q01650 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31520067 1.00 KMO (0.51) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL30852338 1.00 KMO (0.51) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL30852376 1.00 KMO (0.51) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL975884 0.83 KDM4E (0.63) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL9039079 0.81 KDM4E (0.50) KMOKDM4EHIF1ATDP1KYNU
SCHEMBL9340027 0.81 KDM4E (0.47) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL31520062 0.78 KDM4E (0.70) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL31520061 0.78 KDM4E (0.70) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL7415550 0.78 KMO (0.51) KMOKDM4EHIF1ATDP1GRIK1
SCHEMBL30852411 0.78 KDM4E (0.70) KMOKDM4EHIF1ATDP1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240188613-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-06-13 — — US claimed
US-20240090547-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-03-21 — — US claimed
US-20240065302-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-02-29 — — US claimed
CN-117098460-A Sweetener composition comprising mogrosides and uses thereof 弗门尼舍公司 2023-11-21 — — CN claimed
CN-116997263-A Sweetener compositions comprising siamenoside I and uses thereof 弗门尼舍公司 2023-11-03 — — CN claimed
CN-116963609-A Sweetener composition comprising mogrosides and uses thereof 弗门尼舍公司 2023-10-27 — — CN claimed
EP-4258896-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
EP-4258895-A1 SWEETENER COMPOSTIONS COMPRISING SIAMENOSIDE I AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
EP-4258897-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
WO-2022155668-A1 SWEETENER COMPOSTIONS COMPRISING SIAMENOSIDE I AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
WO-2022155667-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
WO-2022155669-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
US-20180086751-A1 SWEETENER COMPOSITION SENOMYX, INC. 2018-03-29 — — US claimed
US-20170354175-A1 SWEETENER COMPOSITION SENOMYX, INC. 2017-12-14 — — US claimed
US-20170105432-A1 SWEETENER AND FLAVOR ENHANCER FORMULATIONS SENOMYX, INC. 2017-04-20 — — US claimed
US-8053585-B2 Protecting group for carboxylic acids that can be photolyzed by visible light CORNELL RESEARCH FOUNDATION, INC. (US) 2011-11-08 — — US claimed
US-20070243519-A1 Protecting group for carboxylic acids that can be photolyzed by visible light CORNELL RESEARCH FOUNDATION, INC. (US) 2007-10-18 — — US claimed
US-5587509-A Caged caboxyl compounds and use thereof CORNELL RESEARCH FOUNDATION, INC. (US) 1996-12-24 — — US claimed
US-5430175-A Caged carboxyl compounds and use thereof CORNELL RESEARCH FOUNDATION, INC. (US) 1995-07-04 — — US claimed
WO-1995015305-A1 CAGED CARVOXYL COMPOUNDS AND THEIR USE IN CHEMICAL KINETIC INVESTIGATION OF NEUROTRANSMITTER RECEPTORS CORNELL RESEARCH FOUNDATION, INC. (US) 1995-06-08 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180086751-A1 SWEETENER COMPOSITION TAS2R50, TAS1R2, TAS2R10 KMO 3517/4885KDM4E 2019/4885HIF1A 3959/4885
US-20170105432-A1 SWEETENER AND FLAVOR ENHANCER FORMULATIONS TAS2R50, TAS2R10, TAS2R40 KMO 3611/4885KDM4E 980/4885HIF1A 3092/4885
US-20070243519-A1 Protecting group for carboxylic acids that can be photolyzed by visible light CYBA, ALDH3A1, HCCS KMO 289/4885KDM4E 2126/4885HIF1A 2082/4885
US-20170354175-A1 SWEETENER COMPOSITION TAS1R2, TAS1R1, TAS2R50 KMO 3749/4885KDM4E 2566/4885HIF1A 3962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.