Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR2A | P27037 | 4/20 | 0.41 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 4/20 | 0.31 |
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30852903 | 0.81 | ACVR2A (0.37) | ACVR2ATGFBR2KDM4EALDH1A1HPGD | |
| SCHEMBL30852920 | 0.81 | ACVR2A (0.37) | ACVR2ATGFBR2PDE10AKDM4EALDH1A1 | |
| SCHEMBL30852973 | 0.81 | ACVR2A (0.38) | ACVR2ATGFBR2KDM4EALDH1A1HPGD | |
| SCHEMBL30852885 | 0.73 | ACVR2A (0.41) | ACVR2ATGFBR2PDE10AKDM4EALDH1A1 | |
| SCHEMBL31639341 | 0.72 | PDE10A (0.34) | ACVR2ATGFBR2PDE10AKDM4EALDH1A1 | |
| SCHEMBL30632316 | 0.71 | JUND (0.34) | ACVR2ATGFBR2PDE10AKDM4EALDH1A1 | |
| SCHEMBL31639231 | 0.69 | HPGD (0.34) | ACVR2ATGFBR2PDE10AKDM4EALDH1A1 | |
| SCHEMBL31639301 | 0.69 | KDM4E (0.34) | PDE10AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL31639289 | 0.68 | KDM4E (0.36) | PDE10AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL30698334 | 0.67 | KDM4E (0.32) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598539-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076614-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-04-11 | — | — | WO | disclosed |