Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639301 | 0.88 | KDM4E (0.34) | HPGDKDM4EALDH1A1DRD2HTR1A | |
| SCHEMBL31639434 | 0.84 | KDM4E (0.32) | HPGDKDM4EALDH1A1DRD2HTR1A | |
| SCHEMBL31639341 | 0.82 | PDE10A (0.34) | HPGDKDM4EALDH1A1MEN1TSHR | |
| SCHEMBL31639113 | 0.77 | KDM4E (0.50) | HPGDKDM4EALDH1A1TSHRKMT2A | |
| SCHEMBL31639289 | 0.76 | KDM4E (0.36) | HPGDKDM4EALDH1A1MEN1TSHR | |
| SCHEMBL30632316 | 0.72 | JUND (0.34) | HPGDKDM4EALDH1A1MEN1TSHR | |
| SCHEMBL24542494 | 0.71 | CHRM5 (0.40) | ADRA1APDE10AACVR2ATGFBR2LRRK2 | |
| SCHEMBL30698334 | 0.70 | KDM4E (0.32) | KDM4EALDH1A1MAPT | |
| SCHEMBL31000185 | 0.70 | ACVR2A (0.32) | ACVR2ATGFBR2LRRK2 | |
| SCHEMBL30852941 | 0.69 | ACVR2A (0.41) | HPGDKDM4EALDH1A1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |