Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.42 |
| ▸ | SRC | P12931 | 9/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24752055 | 1.00 | ABL1 (0.42) | ABL1SRCXDHMAPK1CYP1A2 | |
| SCHEMBL29763764 | 0.85 | MEN1 (0.46) | KDM4E | |
| SCHEMBL24752128 | 0.85 | MEN1 (0.46) | KDM4E | |
| SCHEMBL24752309 | 0.84 | MEN1 (0.39) | KDM4E | |
| SCHEMBL10323979 | 0.82 | DYRK1A (0.45) | KDM4ETP53 | |
| SCHEMBL28705638 | 0.81 | FGFR1 (0.40) | — | |
| SCHEMBL20980339 | 0.81 | KDM4E (0.43) | MAPK1KDM4E | |
| SCHEMBL28514657 | 0.79 | MEN1 (0.35) | KDM4E | |
| SCHEMBL18940570 | 0.79 | ABL1 (0.49) | ABL1SRCXDHMAPK1CYP1A2 | |
| SCHEMBL24752125 | 0.75 | GABRP (0.37) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010951-A | New preparation method of reboxetine | 上海上药第一生化药业有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-117881681-A | Substituted pyrrolo [2,3-d ] pyrimidines, their preparation and their therapeutic use | 赛诺菲 | 2024-04-12 | — | — | CN | disclosed |