Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 11/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 8/20 | 0.46 |
| ▸ | PDE1A | P54750 | 6/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 6/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK1 | P23458 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30853339 | 0.78 | JAK2 (0.49) | PDE9AJAK2JAK1JAK3 | |
| SCHEMBL22042902 | 0.77 | PDE9A (0.52) | PDE9APDE1CPDE1APDE1BPDE4D | |
| SCHEMBL19434476 | 0.77 | PDE9A (0.52) | PDE9APDE1CPDE1APDE1BPDE4D | |
| SCHEMBL1742197 | 0.75 | PDE9A (0.54) | PDE9APDE1C | |
| SCHEMBL29413167 | 0.74 | PDE1C (0.54) | PDE9APDE1CPDE1APDE1BPDE4D | |
| SCHEMBL15910836 | 0.71 | DDB1 (0.51) | PDE9APDE1CPDE1APDE1BPDE4D | |
| SCHEMBL17603784 | 0.70 | PDE9A (0.61) | PDE9APDE1C | |
| SCHEMBL30896400 | 0.69 | PDE1C (0.46) | PDE9APDE1CPDE1APDE1BPDE4D | |
| SCHEMBL14771558 | 0.69 | PDE9A (0.66) | PDE9APDE1C | |
| SCHEMBL24968162 | 0.67 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |