Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.39 |
| ▸ | BRD4 | O60885 | 4/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 3/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | TAF1 | P21675 | 2/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27186103 | 0.88 | CECR2 (0.36) | BRD4CECR2TAF1BRD9 | |
| SCHEMBL27186295 | 0.85 | PIM3 (0.39) | BRD4CECR2TAF1BRD9 | |
| SCHEMBL30853329 | 0.75 | BTK (0.37) | BTK | |
| SCHEMBL29844397 | 0.68 | BTK (0.41) | BTKBRD4CECR2TAF1BRD9 | |
| SCHEMBL30853365 | 0.68 | BTK (0.39) | BTKBRD4CECR2PDPK1 | |
| SCHEMBL9965010 | 0.66 | BTK (0.65) | BTKPDPK1 | |
| SCHEMBL21481676 | 0.64 | BTK (0.55) | BTKBRD4PDPK1 | |
| SCHEMBL16382696 | 0.64 | BTK (0.55) | BTKPDPK1 | |
| SCHEMBL16382682 | 0.64 | BTK (0.48) | BTKPDPK1 | |
| SCHEMBL27186168 | 0.63 | NOTUM (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |