Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760501 | 0.78 | UCHL1 (0.45) | HIF1AKMT2A | |
| SCHEMBL17921438 | 0.76 | DGAT1 (0.34) | DGAT1HIF1AKMT2A | |
| SCHEMBL17092773 | 0.75 | KDM4E (0.42) | DGAT1KMT2A | |
| SCHEMBL24745608 | 0.74 | RAB9A (0.35) | DGAT1HIF1AKMT2A | |
| SCHEMBL30572614 | 0.73 | DHODH (0.38) | DGAT1 | |
| SCHEMBL20482359 | 0.73 | DHODH (0.38) | DGAT1 | |
| SCHEMBL17071940 | 0.71 | DGAT1 (0.40) | DGAT1FFAR1PDGFRBKDRHIF1A | |
| SCHEMBL3374281 | 0.70 | BRD4 (0.43) | DGAT1FFAR1HIF1AKMT2A | |
| SCHEMBL26660219 | 0.70 | DGAT1 (0.44) | DGAT1PDGFRBKDRHIF1A | |
| SCHEMBL25035049 | 0.70 | HIF1A (0.43) | DGAT1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |