Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17641542 | 1.00 | KDM4E (0.62) | KDM4EHIF1ATDP1G6PDCASP7 | |
| SCHEMBL14645210 | 0.82 | ALDH1A1 (0.46) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL3156486 | 0.82 | ALDH1A1 (0.46) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL31520049 | 0.82 | ALDH1A1 (0.46) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL29934345 | 0.77 | KDM4E (1.00) | KDM4EHIF1ATDP1G6PDCASP7 | |
| SCHEMBL134058 | 0.77 | KDM4E (1.00) | KDM4EHIF1ATDP1G6PDCASP7 | |
| SCHEMBL29352838 | 0.77 | KDM4E (1.00) | KDM4EHIF1ATDP1G6PDCASP7 | |
| SCHEMBL29375641 | 0.77 | KDM4E (1.00) | KDM4EHIF1ATDP1G6PDCASP7 | |
| SCHEMBL180582 | 0.77 | KDM4E (1.00) | KDM4EHIF1ATDP1G6PDCASP7 | |
| SCHEMBL30973707 | 0.77 | KDM4E (1.00) | KDM4EHIF1ATDP1G6PDCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572737-A1 | METHODS OF USING A SMALL MOLECULE CHEMICAL COMPOUND TO REDUCE THE APPEARANCE OF RHYTIDS AND WRINKLES | Birchbiomed Inc. (CA) | 2025-06-25 | — | — | EP | claimed |
| WO-2024055116-A1 | METHODS OF USING A SMALL MOLECULE CHEMICAL COMPOUND TO REDUCE THE APPEARANCE OF RHYTIDS AND WRINKLES | BIRCHBIOMED INC. (CA) | 2024-03-21 | — | — | WO | claimed |
| US-12551459-B2 | Combination of kynurenine and antigen presenting cells (APC) as therapeutics and methods for their use in immune modulation | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2026-02-17 | — | — | US | disclosed |
| EP-4572737-A1 | METHODS OF USING A SMALL MOLECULE CHEMICAL COMPOUND TO REDUCE THE APPEARANCE OF RHYTIDS AND WRINKLES | Birchbiomed Inc. (CA) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024055116-A1 | METHODS OF USING A SMALL MOLECULE CHEMICAL COMPOUND TO REDUCE THE APPEARANCE OF RHYTIDS AND WRINKLES | BIRCHBIOMED INC. (CA) | 2024-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12551459-B2 | Combination of kynurenine and antigen presenting cells (APC) as therapeutics and methods for their use in immune modulation | AADAT, IDO1, IAPP | KDM4E 1466/4885HIF1A 1602/4885TDP1 3336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.