SCHEMBL30853597

SCHEMBL30853597

CCCCOC(=O)N1Cc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2C1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29597075 0.86 RBP4 (0.60) RBP4
SCHEMBL17505268 0.86 RBP4 (0.60) RBP4
SCHEMBL17505280 0.86 RBP4 (0.71) RBP4
SCHEMBL29597989 0.86 RBP4 (0.71) RBP4
SCHEMBL29598011 0.84 RBP4 (0.70) RBP4
SCHEMBL17505320 0.84 RBP4 (0.70) RBP4
SCHEMBL20696243 0.84 RBP4 (0.60) RBP4
SCHEMBL29596986 0.84 RBP4 (0.62) RBP4
SCHEMBL17505223 0.84 RBP4 (0.62) RBP4
SCHEMBL20525332 0.84 RBP4 (0.64) RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11919913-B2 4-phenylpiperidines, their preparation and use THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11919913-B2 4-phenylpiperidines, their preparation and use HTR3C, HRH4, CYP4F3 RBP4 2807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.