Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | GHSR | Q92847 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255660 | 1.00 | ALDH1A1 (0.72) | ALDH1A1POLBTSHRSLC40A1MEN1 | |
| SCHEMBL11973840 | 0.85 | MEN1 (0.63) | ALDH1A1POLBTSHRSLC40A1MEN1 | |
| SCHEMBL22234047 | 0.82 | GAA (0.71) | ALDH1A1POLBSLC40A1MEN1KMT2A | |
| SCHEMBL29540765 | 0.82 | GAA (0.71) | ALDH1A1POLBSLC40A1MEN1KMT2A | |
| SCHEMBL11972879 | 0.81 | SLC40A1 (1.00) | ALDH1A1POLBTSHRSLC40A1MEN1 | |
| SCHEMBL30854810 | 0.81 | MEN1 (0.67) | ALDH1A1POLBSLC40A1MEN1KMT2A | |
| SCHEMBL29255669 | 0.81 | MEN1 (0.67) | ALDH1A1POLBSLC40A1MEN1KMT2A | |
| SCHEMBL11973822 | 0.81 | SLC40A1 (0.64) | ALDH1A1POLBTSHRSLC40A1MEN1 | |
| SCHEMBL22076981 | 0.81 | MEN1 (1.00) | POLBTSHRSLC40A1MEN1KMT2A | |
| SCHEMBL1507919 | 0.80 | SLC40A1 (0.76) | ALDH1A1POLBSLC40A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865886-B | N- (quinoline-8-yl) quinoline-8-sulfonamide compound and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-117865886-A | N- (quinoline-8-yl) quinoline-8-sulfonamide compound and application thereof | 中国药科大学 | 2024-04-12 | — | — | CN | disclosed |