Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | EPOR | P19235 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3025733 | 1.00 | KMT2A (0.55) | KMT2ASMN1; SMN2ALOX5MAOBLTA4H | |
| SCHEMBL21656313 | 0.83 | L3MBTL1 (0.50) | — | |
| SCHEMBL30854879 | 0.82 | CACNA1B (0.45) | SMN1; SMN2ALOX5ACACBSMPD1 | |
| SCHEMBL3026700 | 0.82 | CACNA1B (0.45) | SMN1; SMN2ALOX5ACACBSMPD1 | |
| SCHEMBL14699488 | 0.81 | KMT2A (0.55) | KMT2ASMN1; SMN2ALOX5MAOBLTA4H | |
| SCHEMBL14699489 | 0.81 | KMT2A (0.55) | KMT2ASMN1; SMN2ALOX5MAOBLTA4H | |
| SCHEMBL15268712 | 0.81 | SLC6A2 (0.42) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3028651 | 0.80 | ROCK2 (0.42) | — | |
| SCHEMBL30854880 | 0.80 | ROCK2 (0.42) | — | |
| SCHEMBL31724359 | 0.79 | SYK (0.51) | KMT2ASMN1; SMN2ALOX5MAOBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865843-A | Nicotinamide derivatives for the preparation of sodium and/or calcium channel modulators | 赛诺金医药科技(无锡)有限公司 | 2024-04-12 | — | — | CN | disclosed |