Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP1 | P07148 | 1/20 | 0.56 |
| ▸ | FABP6 | P51161 | 1/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15721555 | 0.82 | ACHE (0.64) | FABP1FABP6ACHENOS2MAPT | |
| SCHEMBL10054969 | 0.81 | FABP1 (0.79) | FABP1FABP6CXCR4KDM4ENPC1 | |
| SCHEMBL30438836 | 0.79 | PRMT6 (0.63) | PRMT6MAP4K4KDM4EAGXTGAA | |
| SCHEMBL30438654 | 0.78 | PRMT6 (0.58) | PRMT6MAP4K4KDM4EAGXTDRD2 | |
| SCHEMBL4718827 | 0.77 | FABP1 (0.67) | FABP1FABP6CXCR4KDM4ENPC1 | |
| SCHEMBL15721559 | 0.77 | ADORA2A (0.50) | ACHEKDM4ENPC1RAB9ATP53 | |
| SCHEMBL30854990 | 0.76 | PRMT6 (0.53) | PRMT6MAP4K4ACHEKDM4EAGXT | |
| SCHEMBL30438815 | 0.76 | PRMT6 (0.53) | PRMT6MAP4K4ACHEKDM4EAGXT | |
| SCHEMBL28724962 | 0.76 | CXCR4 (0.58) | FABP1FABP6CXCR4ACHEKDM4E | |
| SCHEMBL30854964 | 0.74 | CXCR4 (0.64) | FABP1FABP6CXCR4ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |