Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.49 |
| ▸ | MEF2D | Q14814 | 4/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855025 | 0.88 | PLOD2 (0.54) | PRMT6MAPTKDM4EALOX12HTT | |
| SCHEMBL30854948 | 0.88 | KDM4E (0.69) | MAPTKDM4EALOX12HTTHDAC4 | |
| SCHEMBL30438836 | 0.87 | PRMT6 (0.63) | PRMT6MAPTKDM4EALOX12HTT | |
| SCHEMBL2987241 | 0.83 | PRMT6 (0.58) | PRMT6MAPTKDM4EALOX12HTT | |
| SCHEMBL30438522 | 0.82 | KDM4E (0.68) | MAPTKDM4EALOX12HTTALDH1A1 | |
| SCHEMBL14680275 | 0.79 | MAPT (0.78) | MAPTKDM4EALOX12HTTALDH1A1 | |
| SCHEMBL30854955 | 0.78 | FABP1 (0.56) | PRMT6MAPTKDM4EHDAC4MEF2D | |
| SCHEMBL30854990 | 0.76 | PRMT6 (0.53) | PRMT6KDM4EHDAC4MEF2DMAP4K4 | |
| SCHEMBL30438815 | 0.76 | PRMT6 (0.53) | PRMT6MAPTKDM4EALOX12HDAC4 | |
| SCHEMBL6755669 | 0.75 | ADRA2B (0.54) | PRMT6F2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |