Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855028 | 0.89 | SMN1; SMN2 (0.51) | MAPTKDM4EALOX12HTTL3MBTL1 | |
| SCHEMBL30855001 | 0.86 | NCF1 (0.51) | KDM4ERAB9AL3MBTL1GAANPC1 | |
| SCHEMBL30854953 | 0.86 | AGXT (0.48) | MAPTKDM4EALOX12HTTALDH1A1 | |
| SCHEMBL899406 | 0.79 | CYP1A1 (0.67) | MAPTRAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL30855012 | 0.74 | MAPT (0.89) | MAPTKDM4EALOX12HTTRAB9A | |
| SCHEMBL30854964 | 0.74 | CXCR4 (0.64) | MAPTKDM4EALOX12HTTRAB9A | |
| SCHEMBL30854968 | 0.74 | KDM4E (0.57) | MAPTKDM4EALOX12HTTRAB9A | |
| SCHEMBL15545775 | 0.74 | CYP1A2 (0.57) | MAPTKDM4EALOX12HTTRAB9A | |
| SCHEMBL30854990 | 0.74 | PRMT6 (0.53) | KDM4EL3MBTL1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL171893 | 0.73 | KDM4E (0.62) | KDM4ERAB9AL3MBTL1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |