Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 7/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654046 | 0.81 | CYP1B1 (1.00) | CYP1A1CYP1A2CYP1B1ALOX5 | |
| SCHEMBL9381614 | 0.81 | RAB9A (0.65) | CYP1A1CYP1A2CYP1B1MAPTNPC1 | |
| Water SCHEMBL9387383 | 0.80 | RAB9A (0.64) | CYP1A1CYP1A2CYP1B1MAPTNPC1 | |
| SCHEMBL30855003 | 0.79 | MAPT (0.56) | CYP1A1CYP1A2CYP1B1MAPTNPC1 | |
| SCHEMBL31231876 | 0.78 | CYP1A2 (0.44) | CYP1A1CYP1A2CYP1B1MAPTNPC1 | |
| SCHEMBL7980595 | 0.77 | MAPT (0.62) | CYP1A2MAPTNPC1POLBRAB9A | |
| SCHEMBL2931477 | 0.77 | CBFB (0.51) | CYP1A1CYP1A2CYP1B1MAPTNPC1 | |
| SCHEMBL29972048 | 0.75 | PLK4 (0.68) | MAPTSYKPLK4TP53MAPK1 | |
| SCHEMBL30854958 | 0.74 | MAPT (0.65) | CYP1A1CYP1A2CYP1B1MAPTNPC1 | |
| SCHEMBL15545775 | 0.74 | CYP1A2 (0.57) | CYP1A1CYP1A2CYP1B1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |