Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.37 |
| ▸ | PRKX | P51817 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | MST1R | Q04912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31620477 | 0.86 | TSHR (0.40) | LRRK2DAPK3MAP4K4FLT3CSNK1A1 | |
| SCHEMBL11577272 | 0.71 | PLK4 (0.44) | LRRK2DAPK3MAP4K4FLT3CSNK1A1 | |
| SCHEMBL2427163 | 0.70 | LRRK2 (0.42) | LRRK2DAPK3MAP4K4FLT3CSNK1A1 | |
| SCHEMBL18188363 | 0.70 | PLK4 (0.42) | LRRK2DAPK3MAP4K4FLT3CSNK1A1 | |
| SCHEMBL4501756 | 0.70 | PLK4 (0.42) | LRRK2DAPK3MAP4K4FLT3CSNK1A1 | |
| SCHEMBL1601328 | 0.70 | CTNNB1 (0.47) | MAP4K4CDK5CLK4CHEK1FGFR1 | |
| SCHEMBL2582880 | 0.70 | MAPT (0.46) | LRRK2DAPK3MAP4K4FLT3CSNK1A1 | |
| SCHEMBL4083786 | 0.70 | NOS1 (0.38) | LRRK2DAPK3MAP4K4FLT3CSNK1A1 | |
| SCHEMBL4071766 | 0.70 | CYP1A2 (0.39) | LRRK2DAPK3MAP4K4FLT3CSNK1A1 | |
| SCHEMBL31404481 | 0.70 | RXRA (0.43) | LRRK2DAPK3MAP4K4FLT3CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152713-A | Tricyclic aryl derivatives and compositions and methods thereof | 昂胜医疗科技公司 | 2025-06-13 | — | — | CN | disclosed |
| EP-4561562-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026128-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |