Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250100 | 0.78 | AKR1B1 (0.38) | CYP1A2MAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL470187 | 0.72 | ALDH1A1 (0.34) | CYP1A2MAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL30811696 | 0.72 | CYP3A4 (0.40) | MAPTCYP3A4LMNAHPGDGRIA1 | |
| SCHEMBL30856077 | 0.72 | CYP1A2 (0.51) | CYP1A2MAPTCYP3A4TSHRBLM | |
| SCHEMBL27096286 | 0.70 | CYP1A2 (0.67) | CYP1A2MAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL29478827 | 0.70 | CYP1A2 (0.67) | CYP1A2MAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL22655651 | 0.69 | MAPT (0.39) | CYP1A2MAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2215478 | 0.69 | TDO2 (0.46) | PIM1PIM3NOS1 | |
| SCHEMBL27264780 | 0.68 | CYP1A2 (0.59) | CYP1A2MAPTCYP3A4TSHRLMNA | |
| SCHEMBL30217347 | 0.68 | CYP1A2 (0.59) | CYP1A2MAPTCYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152713-A | Tricyclic aryl derivatives and compositions and methods thereof | 昂胜医疗科技公司 | 2025-06-13 | — | — | CN | disclosed |
| EP-4561562-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026128-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |