Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29195485 | 1.00 | HRH4 (0.39) | HRH4KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL24815805 | 0.83 | KMT2A (0.41) | HRH4KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL29195509 | 0.78 | GRIN2D (0.53) | HRH4KDM4EHSD17B10ALDH1A1CRHBP | |
| SCHEMBL30788620 | 0.77 | HRH4 (0.58) | HRH4KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL22148449 | 0.77 | HRH4 (0.58) | HRH4KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL22119420 | 0.68 | NOS3 (0.44) | HRH4KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL31470240 | 0.68 | KMT2A (0.35) | HRH4KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL11898909 | 0.67 | KMT2A (0.68) | HRH4KMT2AHSD17B10MEN1ALDH1A1 | |
| SCHEMBL31120933 | 0.67 | NOS3 (0.38) | HRH4KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL29187344 | 0.67 | NOS3 (0.41) | HRH4KDM4EKMT2AHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917405-A | KIF18A protein inhibitors | 杭州邦顺制药有限公司 | 2024-04-23 | — | — | CN | disclosed |