Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | CDK9 | P50750 | 3/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17678354 | 0.83 | CYP11B2 (0.58) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL13527908 | 0.82 | KDM4E (0.75) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL30847394 | 0.81 | CDK9 (0.51) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL17678202 | 0.81 | CDK9 (0.51) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL1391258 | 0.80 | KDM4E (0.97) | KDM4EALDH1A1MAPTGFERTDP1 | |
| Hydrochloric Acid SCHEMBL15544554 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL27120383 | 0.78 | CDK9 (0.49) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL21025787 | 0.78 | CYP11B2 (0.49) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL23459663 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL8130710 | 0.77 | CYP11B2 (0.64) | KDM4EALDH1A1MAPTGFERTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917405-A | KIF18A protein inhibitors | 杭州邦顺制药有限公司 | 2024-04-23 | — | — | CN | disclosed |