Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 12/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.49 |
| ▸ | CDK9 | P50750 | 2/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130710 | 0.87 | CYP11B2 (0.64) | CYP11B2CYP11B1CDK9CCNT1CYP19A1 | |
| SCHEMBL17586640 | 0.81 | CYP11B2 (0.58) | CYP11B2CYP11B1CDK9CCNT1CYP19A1 | |
| SCHEMBL17678354 | 0.81 | CYP11B2 (0.58) | CYP11B2CYP11B1CDK9CCNT1CYP19A1 | |
| SCHEMBL30847394 | 0.78 | CDK9 (0.51) | CYP11B2CYP11B1CDK9CCNT1CYP19A1 | |
| SCHEMBL30856700 | 0.78 | KDM4E (0.65) | CYP11B2CYP11B1CDK9CCNT1CYP19A1 | |
| SCHEMBL17678202 | 0.78 | CDK9 (0.51) | CYP11B2CYP11B1CDK9CCNT1CYP19A1 | |
| SCHEMBL31587638 | 0.76 | AKT1 (0.45) | CYP11B2CYP11B1CDK9CCNT1ALDH1A1 | |
| SCHEMBL27120383 | 0.76 | CDK9 (0.49) | CYP11B2CYP11B1CDK9CCNT1CYP19A1 | |
| SCHEMBL8279311 | 0.76 | ESRRA (0.52) | CDK9KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL9673866 | 0.74 | CCR5 (0.60) | CYP11B2CYP11B1CDK9CCNT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190151312-A1 | HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES | BIOMARIN PHARMACEUTICAL INC. | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151312-A1 | HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES | HPSE, GAA, MAN2B1 | CYP11B2 1253/4885CYP11B1 1085/4885CDK9 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.