Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 9/20 | 0.47 |
| ▸ | VEGFA | P15692 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 9/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556069 | 1.00 | EPAS1 (0.47) | EPAS1VEGFAARCYP19A1MRGPRX4 | |
| SCHEMBL922922 | 0.77 | AR (0.50) | EPAS1VEGFAAR | |
| SCHEMBL8549500 | 0.76 | SCN9A (0.54) | EPAS1VEGFAARCYP19A1MRGPRX4 | |
| SCHEMBL891091 | 0.75 | L3MBTL1 (0.65) | EPAS1VEGFAARMRGPRX4 | |
| SCHEMBL15832067 | 0.74 | AR (0.54) | EPAS1VEGFAAR | |
| SCHEMBL2747584 | 0.73 | EGFR (0.50) | EPAS1VEGFAARCYP19A1MRGPRX4 | |
| SCHEMBL14663781 | 0.72 | EPAS1 (0.49) | EPAS1VEGFAARMRGPRX4 | |
| SCHEMBL14662039 | 0.72 | AR (0.54) | EPAS1VEGFAARMRGPRX4 | |
| SCHEMBL31448622 | 0.72 | EPAS1 (0.50) | EPAS1VEGFAARCYP19A1 | |
| SCHEMBL16555547 | 0.71 | EPAS1 (0.71) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49948-E1 | Aryl ethers and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2024-04-30 | — | — | US | disclosed |