SCHEMBL922922

SCHEMBL922922

N#Cc1cccc(Oc2ccccc2C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AR P10275 15/20 0.50
EPAS1 Q99814 3/20 0.50
VEGFA P15692 1/20 0.49
MEN1 O00255 1/20 0.46
CNR1 P21554 1/20 0.46
GPR183 P32249 1/20 0.46
CNR2 P34972 1/20 0.46
KMT2A Q03164 1/20 0.46
SLC22A12 Q96S37 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8432193 0.84 AR (0.55) AREPAS1VEGFASLC22A12
SCHEMBL8549500 0.83 SCN9A (0.54) AREPAS1VEGFAMEN1CNR1
SCHEMBL15832067 0.82 AR (0.54) AREPAS1VEGFA
SCHEMBL29788295 0.81 MRGPRX4 (0.47) ARSLC22A12
SCHEMBL23409847 0.81 MRGPRX4 (0.47) ARSLC22A12
SCHEMBL7070086 0.80 MEN1 (0.58) AREPAS1VEGFAMEN1CNR1
SCHEMBL14663781 0.80 EPAS1 (0.49) AREPAS1VEGFA
SCHEMBL14662039 0.80 AR (0.54) AREPAS1VEGFA
SCHEMBL922800 0.80 EPAS1 (0.47) AREPAS1VEGFASLC22A12
SCHEMBL4177578 0.79 AR (0.77) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 AR 4285/4885EPAS1 2104/4885VEGFA 4619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.