Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.54 |
| ▸ | AR | P10275 | 9/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.48 |
| ▸ | VEGFA | P15692 | 1/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15832067 | 0.83 | AR (0.54) | SCN9AAREPAS1VEGFA | |
| SCHEMBL922922 | 0.83 | AR (0.50) | AREPAS1VEGFAMEN1CNR1 | |
| SCHEMBL23409847 | 0.83 | MRGPRX4 (0.47) | SCN9AARMRGPRX4TRPV4 | |
| SCHEMBL29788295 | 0.83 | MRGPRX4 (0.47) | SCN9AARMRGPRX4TRPV4 | |
| SCHEMBL805917 | 0.82 | SCN9A (0.52) | SCN9AARMRGPRX4TRPV4 | |
| SCHEMBL14662039 | 0.81 | AR (0.54) | SCN9AARMRGPRX4EPAS1VEGFA | |
| SCHEMBL14663781 | 0.81 | EPAS1 (0.49) | SCN9AARMRGPRX4EPAS1VEGFA | |
| SCHEMBL8544623 | 0.79 | AR (0.54) | AREPAS1VEGFACYP19A1 | |
| SCHEMBL523319 | 0.77 | ESRRB (0.51) | ARMRGPRX4TRPV4 | |
| SCHEMBL22731288 | 0.77 | TRPV4 (0.49) | SCN9AARMRGPRX4TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |