Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616963 | 0.87 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL1114114 | 0.86 | SLC6A3 (0.63) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL28412588 | 0.84 | PTGS2 (0.43) | SLC6A3SLC6A4SLC6A2PTGS1PTGS2 | |
| SCHEMBL14920503 | 0.82 | SLC6A3 (0.44) | SLC6A3SLC6A4SLC6A2PTGS1PTGS2 | |
| SCHEMBL524482 | 0.75 | SLC6A3 (0.63) | SLC6A3SLC6A4SLC6A2PTGS1PTGS2 | |
| SCHEMBL16037864 | 0.75 | SLC6A3 (0.43) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL14920438 | 0.73 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL22325333 | 0.73 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL30857682 | 0.72 | SLC6A3 (0.63) | SLC6A3SLC6A4SLC6A2PTGS1PTGS2 | |
| SCHEMBL16038213 | 0.72 | SLC6A3 (0.43) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067818-A1 | CHIMERIC COMPOUND USED FOR TARGETED DEGRADATION OF BCL-2 PROTEIN, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |