Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 6/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29290360 | 0.79 | CYP1A2 (0.53) | NPSR1CNR2CYP2C19SMN1; SMN2CCR4 | |
| Trifluoroacetic Acid SCHEMBL4829974 | 0.77 | PTGER4 (0.50) | PTGER4CNR2 | |
| SCHEMBL10154052 | 0.76 | NPSR1 (0.65) | NPSR1KMT2ACNR2SMN1; SMN2CCR4 | |
| SCHEMBL14242685 | 0.76 | SPHK1 (0.54) | NPSR1KMT2ACNR2CYP2C19SMN1; SMN2 | |
| SCHEMBL26999849 | 0.76 | KMT2A (0.48) | ELANEKMT2ASMN1; SMN2 | |
| SCHEMBL29641544 | 0.75 | OPRM1 (0.56) | ELANECTSG | |
| SCHEMBL30440339 | 0.75 | OPRM1 (0.56) | ELANECTSG | |
| Trifluoroacetic Acid SCHEMBL4372725 | 0.74 | NPSR1 (0.48) | PTGER4NPSR1CNR2CCR4 | |
| Trifluoroacetic Acid SCHEMBL4376570 | 0.74 | NPSR1 (0.48) | PTGER4NPSR1CNR2CCR4 | |
| SCHEMBL7315812 | 0.74 | CTRB1 (0.67) | ELANENPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619037-A1 | SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT | Lerchen, Hans-Georg (DE) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024105197-A1 | SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT | VINCERX PHARMA GMBH (DE) | 2024-05-23 | — | — | WO | disclosed |