Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | CCR4 | P51679 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | WNT3 | P56703 | 1/20 | 0.39 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4372725 | 1.00 | NPSR1 (0.48) | NPSR1CTSCCCR4CNR2CACNA1G | |
| Trifluoroacetic Acid SCHEMBL29290360 | 0.79 | CYP1A2 (0.53) | NPSR1CCR4CNR2CACNA1GSPHK1 | |
| SCHEMBL7105021 | 0.77 | F2 (0.49) | NPSR1PTGER4HSD11B1F2 | |
| Hydrochloric Acid SCHEMBL7147052 | 0.76 | F2 (0.51) | NPSR1PTGER4HSD11B1F2 | |
| Trifluoroacetic Acid SCHEMBL4372721 | 0.75 | ALDH1A1 (0.56) | HTR2CHTR2BCHRM3F2 | |
| Trifluoroacetic Acid SCHEMBL4376564 | 0.75 | ALDH1A1 (0.56) | HTR2CHTR2BCHRM3F2 | |
| Trifluoroacetic Acid SCHEMBL30859244 | 0.74 | ELANE (0.50) | NPSR1CCR4CNR2PTGER4 | |
| SCHEMBL10154052 | 0.72 | NPSR1 (0.65) | NPSR1CCR4CNR2CACNA1GOPRL1 | |
| SCHEMBL7452551 | 0.71 | FKBP1A (0.60) | NPSR1CCR4CACNA1GOPRL1OPRK1 | |
| SCHEMBL2441194 | 0.71 | FKBP1A (0.60) | NPSR1CCR4CACNA1GOPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626023-B2 | Compounds for treating tumors | WYETH (US) | 2009-12-01 | — | — | US | disclosed |
| US-20080221181-A1 | COMPOUNDS FOR TREATING TUMORS | WYETH HOLDINGS CORPORATION (US) | 2008-09-11 | — | — | US | disclosed |
| US-7390910-B2 | Compounds for treating tumors | WYETH (US) | 2008-06-24 | — | — | US | disclosed |
| WO-2005016958-A2 | COMPOUNDS FOR TREATING TUMORS | WYETH HOLDINGS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20050037977-A1 | Compounds for treating tumors | WYETH HOLDINGS CORPORATION (US) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221181-A1 | COMPOUNDS FOR TREATING TUMORS | RB1, MRPL9, BCOR | NPSR1 1234/4885CTSC 4700/4885CCR4 2371/4885 |
| US-20050037977-A1 | Compounds for treating tumors | RB1, MRPL9, BCOR | NPSR1 1234/4885CTSC 4700/4885CCR4 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.