SCHEMBL30859564

SCHEMBL30859564

CC(C)(C)OC(=O)N1CCC2(CCC(n3ccc(C(=O)O)c(C=O)c3=O)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 9/20 0.44
HCAR1 Q9BXC0 1/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
USP2 O75604 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PRKCG P05129 1/20 0.36
PRKCB P05771 1/20 0.36
PRKCA P17252 1/20 0.36
PRKCH P24723 1/20 0.36
PRKCE Q02156 1/20 0.36
PRKCD Q05655 1/20 0.36
CCR5 P51681 1/20 0.36
STS P08842 1/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
CRHBP P24387 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27370180 0.91 GPR119 (0.45) GPR119HCAR1PRKCGPRKCBPRKCA
SCHEMBL30859540 0.91 SCD5 (0.35) GPR119HCAR1MEN1KMT2AHPGD
SCHEMBL30859553 0.91 GPR119 (0.42) GPR119MEN1KMT2AHPGDHSD17B10
SCHEMBL27369897 0.90 GPR119 (0.44) GPR119HCAR1MEN1KMT2AHPGD
SCHEMBL30859600 0.85 GPR119 (0.44) GPR119HCAR1MEN1KMT2AHPGD
SCHEMBL30859545 0.83 KRAS (0.37) GPR119HCAR1MEN1KMT2AHPGD
SCHEMBL27370177 0.80 GPR119 (0.44) GPR119HCAR1PRKCGPRKCBPRKCA
SCHEMBL30859580 0.77 CHRM4 (0.31) GPR119MEN1KMT2AHPGDHSD17B10
SCHEMBL30859560 0.76 GPR119 (0.42) GPR119
SCHEMBL30859588 0.76 SCD5 (0.35) GPR119HCAR1MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024073475-A9 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS (US) 2025-04-24 WO disclosed
WO-2024073475-A1 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed