SCHEMBL27369897

SCHEMBL27369897

CC(C)(C)OC(=O)N1CCC(n2ccc(C(=O)O)c(C=O)c2=O)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 3/20 0.44
HCAR1 Q9BXC0 1/20 0.43
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
USP2 O75604 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TP53 P04637 1/20 0.41
PRKCG P05129 1/20 0.41
PRKCB P05771 1/20 0.41
PRKCA P17252 1/20 0.41
PRKCH P24723 1/20 0.41
PRKCE Q02156 1/20 0.41
PRKCD Q05655 1/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
PTPN2 P17706 1/20 0.41
PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30859564 0.90 GPR119 (0.44) GPR119HCAR1KMT2AMEN1HPGD
SCHEMBL30859553 0.87 GPR119 (0.42) GPR119KMT2AMEN1HPGDHSD17B10
SCHEMBL30859540 0.87 SCD5 (0.35) GPR119HCAR1KMT2AMEN1HPGD
SCHEMBL30859545 0.84 KRAS (0.37) GPR119HCAR1KMT2AMEN1HPGD
SCHEMBL30910260 0.83 GPR119 (0.45) GPR119HCAR1KMT2AMEN1HPGD
SCHEMBL27369894 0.83 GPR119 (0.44) GPR119HCAR1KMT2AMEN1HPGD
SCHEMBL27370180 0.81 GPR119 (0.45) GPR119HCAR1PRKCGPRKCBPRKCA
SCHEMBL30859580 0.80 CHRM4 (0.31) GPR119KMT2AMEN1HPGDHSD17B10
SCHEMBL30859604 0.80 GPR119 (0.41) GPR119HCAR1KMT2ATP53PRKCG
SCHEMBL16669964 0.77 EED (0.51) GPR119HCAR1KMT2ATP53PRKCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024073475-A9 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS (US) 2025-04-24 WO disclosed
WO-2024073475-A1 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed
WO-2024073475-A1 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed