SCHEMBL30859624

SCHEMBL30859624

CC(C)CC(S(=O)(=O)c1ccccc1)[Ge](C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LARS1 Q9P2J5 2/20 0.43
PSIP1 O75475 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.38
GBA1 P04062 1/20 0.38
KDM4E B2RXH2 4/20 0.37
HTR6 P50406 1/20 0.37
ALDH1A1 P00352 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
PKM P14618 2/20 0.36
KMT2A Q03164 1/20 0.36
RAB9A P51151 1/20 0.36
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
LMNA P02545 2/20 0.35
KEAP1 Q14145 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30859606 0.84 LARS1 (0.40) LARS1PSIP1SMN1; SMN2KDM4EHTR6
SCHEMBL29171213 0.76 PSIP1 (0.39) PSIP1SMN1; SMN2KDM4EHTR6ALDH1A1
SCHEMBL29171206 0.76 LARS1 (0.44) LARS1PSIP1SMN1; SMN2KDM4EHTR6
SCHEMBL6095331 0.76 LARS1 (0.47) LARS1PSIP1SMN1; SMN2KDM4EHTR6
SCHEMBL6100068 0.71 LARS1 (0.41) LARS1PSIP1SMN1; SMN2KDM4EHTR6
SCHEMBL29171203 0.71 GBA1 (0.41) PSIP1SMN1; SMN2GBA1KDM4EALDH1A1
SCHEMBL30859616 0.71 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL778854 0.71 HTR6 (0.50) PSIP1SMN1; SMN2KDM4EHTR6ALDH1A1
SCHEMBL4327138 0.71 HTR6 (0.50) PSIP1SMN1; SMN2KDM4EHTR6ALDH1A1
SCHEMBL29171200 0.70 ALDH1A1 (0.42) SMN1; SMN2GBA1KDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486929-A Substituted alkyl germanium compound and modularized synthesis method thereof 西安交通大学 2024-02-02 CN disclosed