SCHEMBL30860693

SCHEMBL30860693

C=C(C)COc1ccc2c(c1)COC2=O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 13/20 0.59
MAOB P27338 13/20 0.59
MAPT P10636 4/20 0.52
GAA P10253 2/20 0.52
LMNA P02545 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
PRF1 P14222 1/20 0.45
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
PKM P14618 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALOX12 P18054 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30860695 1.00 MAOA (0.59) MAOAMAOBMAPTGAALMNA
SCHEMBL14782691 0.83 MAOA (0.66) MAOAMAOBMAPTGAALMNA
SCHEMBL75194 0.78 MAPT (0.49) MAOAMAOBMAPTGAALMNA
SCHEMBL2729559 0.77 MAPT (0.64) MAOAMAOBMAPTGAALMNA
SCHEMBL6661823 0.76 PRF1 (0.65) MAOAMAOBMAPTGAALMNA
SCHEMBL2731553 0.75 KCNJ1 (0.54) MAOAMAOBMAPTGAALMNA
SCHEMBL2593009 0.75 MAOA (0.59) MAOAMAOBMAPTGAAKMT2A
SCHEMBL14782541 0.72 MAOA (0.55) MAOAMAOBMAPTGAALMNA
SCHEMBL23963396 0.71 MAOA (0.51) MAOAMAOBMAPTGAALMNA
SCHEMBL14790726 0.71 MAOA (0.48) MAOAMAOBMAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024086644-A1 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS (US) 2024-04-25 WO disclosed