SCHEMBL75194

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2729559	0.85	MAPT (0.64)	MAPTALDH1A1SMN1; SMN2MAOAMAOB
	SCHEMBL802630	0.85	MAPT (0.48)	MAPTALDH1A1SMN1; SMN2HSD17B10KMT2A
	SCHEMBL15292004	0.81	MAPT (0.44)	MAPTALDH1A1SMN1; SMN2HSD17B10KMT2A
	SCHEMBL19645158	0.80	MAOA (0.39)	MAPTALDH1A1SMN1; SMN2MAOAMAOB
	SCHEMBL23963396	0.80	MAOA (0.51)	MAPTALDH1A1SMN1; SMN2MAOAMAOB
	SCHEMBL2604680	0.79	KMT2A (0.48)	MAPTALDH1A1SMN1; SMN2MAOAHSD17B10
	SCHEMBL783519	0.79	KMT2A (0.51)	MAPTALDH1A1SMN1; SMN2HSD17B10GAA
	SCHEMBL18365493	0.78	MAPT (0.60)	MAPTALDH1A1SMN1; SMN2MAOAMAOB
	SCHEMBL30860695	0.78	MAOA (0.59)	MAPTALDH1A1MAOAMAOBGAA
	SCHEMBL30860693	0.78	MAOA (0.59)	MAPTALDH1A1MAOAMAOBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.