Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860738 | 0.78 | FABP4 (0.40) | PIK3CDRAB9AKMT2AMEN1MAPT | |
| SCHEMBL26906693 | 0.78 | FABP4 (0.40) | PTGS2RAB9AKMT2AMEN1MAPT | |
| SCHEMBL13090795 | 0.76 | MEN1 (0.43) | RAB9AKMT2AMEN1MAPTPOLB | |
| SCHEMBL30860742 | 0.74 | MAPT (0.51) | PTGS1PTGS2PIK3CDKMT2AMEN1 | |
| SCHEMBL6970062 | 0.73 | KMT2A (0.39) | PTGS1PTGS2RAB9AKMT2AMEN1 | |
| SCHEMBL7339922 | 0.73 | KMT2A (0.39) | PTGS1PTGS2RAB9AKMT2AMEN1 | |
| SCHEMBL21363749 | 0.73 | CYP3A4 (0.43) | PTGS1PTGS2PIK3CDRAB9AGLO1 | |
| SCHEMBL12017944 | 0.70 | MAPT (0.71) | RAB9AKMT2AMEN1MAPTPOLB | |
| SCHEMBL546296 | 0.70 | MAPT (0.56) | KMT2AMEN1MAPTPOLBMCL1 | |
| SCHEMBL29415600 | 0.70 | MAPT (0.56) | KMT2AMEN1MAPTPOLBMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | disclosed |